NIMR / ACURET TRAININGS

Ethical Issues in Responsible Animal Experimentation -The ETHRANET Series

Ethical Issues in Responsible Animal experimentation [ETHRANET] is a series of training courses set to adequately train and continue to educate with objective assessment for competency of all personnel involved the care and use of lab animals to the scope on ethics and care requirement which must be known, understood and applied by all animal users in accordance to International guidelines and best global practices. ACURET.ORG is making education and training programs available for fascinated participants from across developing countries and is providing a sound basis for responsible use of animals in research, education and testing. These courses are open to professionals from fields of Biomedical Science including biologists, veterinarians, medical practitioners, Animal Scientists, and pharmacologists from across Africa.

This is an avant-garde course designed for participants from developing countries as it promotes an awareness for the assumption of responsibility regarding animal welfare which impacts on the quality research, teaching and testing. The Goal is to train and raise the bar of Africans, skilled with acute awareness of what humane research essentially stands for. The Courses challenges and engages participants in the active process of critical thinking in addition to the acquisition of knowledge and hands-on skill.  The Guiding principles of these courses is that “good animal welfare and humane experimentation herald high quality science”.








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An ACURET-NIMR Collaborative Initiative

 6-Days Intensive Workshop on

ESSENTIALS OF RESPONSIBLE ANIMAL EXPERIMENTATION

–Brain tissue preparation, Sectioning, Staining

Rain 2018 Course: July 23rd -28th 2018

Overview

The quality of research and the welfare of laboratory animals greatly depend on the competence of personnel involved in the care and use of the animals. The availability of education and training programs is providing a sound basis for a responsible use of animals in research. The course is suitably addressed to Graduate and post graduate students, Junior Faculty, Lab animal Technicians and Technologists, Research Associates/Assistant and Lecturers planning to undertake research in biomedicine requiring the use of animal models.

This Basic course on Essentials of Animal Experimentation will involve the didactic presentation of information and theories of animal use that will contribute to the development of proper attitudes toward the use of animals in scientific procedures including respect for animals), in addition to hands-on acquisition of practical knowledge and skills needed for animal handling and the proper conduct of animal experiments. The general principles of the ethical care and use of animals in research, training, and testing will be focused upon with several approaches upon the 3Rs.

Program and Modules of Course
Learning outcome
Learning methods and activities
Certification

What is and why Responsible Animal Experimentation?
Ethics, Animal Welfare and the 3Rs (level 1)
Biomethodology of Rodents (theory & practical)
Working with lab animals – Occupational Health and safety
Brain tissue Preparation, Sectioning and Staining
Analgesia, Anesthesia, HEP and Euthanasia
Alternatives, Design of projects and procedures
Scientific Writing and reporting in Animal Experimentation

After completing the course, the student should be able to:
Identify and describe relevant legislation which regulate the scientific use of animals
Describe the differing views within society concerning the scientific use of animals
Demonstrate a comprehensive understanding of the principle of the 3Rs, list examples of how the 3Rs can be implemented in research projects and list sources of information related to the 3Rs
Describe the severity classification system and give examples of each category
Describe the principle of implementing early humane endpoints and how this implementation can influence animal health and welfare during the course of an experiment
Describe the basic biology of the relevant animal species, including basic anatomy, physiology, reproduction and behaviour; and recognize the importance of attending to biological and behavioural needs
Describe the environmental factors of importance for maintaining an appropriate health status for the animals
List potential human health hazards associated with contact with laboratory animals and describe how these can be prevented
Describe the principles of humane killing and list appropriate euthanasia methods for the relevant animal species
Recognize that the choice of a euthanasia method may influence the scientific outcome
Describe appropriate methods and principles for handling animals, and describe common techniques / procedures, including administration and sampling techniques
Describe and list the types of analgesic drugs that are effective at the different components
Indicate some of the problems associated with pain recognition and pain management in animals

The theoretical teaching will happen intensively during one week.
Teaching methods will include lectures, study groups, quiz and individual assignments. Some activities will include e-based learning tools.

A “Certificate of Training Course in Essentials of Responsible Animal Experimentation” will be issued when the following has been completed: Attendance at the theoretical lectures, completion of the e-learning modules, passed the home assignment and passed the written exam. This Certificate is valid together with a practical training document.

NIMR / ACURET TRAINING REGISTRATION FORM

Title*First Name*Middle Name*Last Name*Degree*

(e.g., BSc, MSc, DVM, MBBS. MBChB, M.D., Ph.D., F.R.C.S.)

Applicant StatusPrincipal InvestigatorVeterinarianResearch ScientistTechnologistAdministratorAnimal technicianAnimal vendorPhysician/SurgeonJunior FacultyGraduate StudentPost DocPhD StudentSenior FacultySupervisorResident/Fellow-in-TrainingNurseAllied Health (i.e.Manufacturer/Industry (i.e.OtherCityMaleFemaleEmail*Additional Email Address(es):Telephone Number /Office*Type of Course*Rain Course 2018Harmattan Course 2019Institution*Type of InstitutionUniversityResearch InstituteNGOHospitalMinistry/LGAOthersStreet Address*CityCountry* Afghanistan Albania Algeria Andorra Angola Antigua and Barbuda Argentina Armenia Aruba Australia Austria Azerbaijan Bahamas Bahrain Bangladesh Barbados Belarus Belgium Belize Benin Bhutan Bolivia Bosnia and Herzegovina Botswana Brazil Brunei Bulgaria Burkina Faso Burma Burundi Cambodia Cameroon Canada Cape Verde Central African Republic Chad Chile China Colombia Comoros Congo Costa Rica Cote d’Ivoire Croatia Cuba Curacao Cyprus Czech Republic Denmark Djibouti Dominica Dominican Republic Ecuador Egypt El Salvador Equatorial Guinea Eritrea Estonia Ethiopia Fiji Finland France Gabon Gambia Georgia Germany Ghana Greece Grenada Guatemala Guinea Guinea-Bissau Guyana Haiti Holy See Honduras Hong Kong Hungary Iceland India Indonesia Iran Iraq Ireland Israel Italy Jamaica Japan Jordan Kazakhstan Kenya Kiribati Korea, North Korea, South Kosovo Kuwait Kyrgyzstan Laos Latvia Lebanon Lesotho Liberia Libya Liechtenstein Lithuania Luxembourg Macau Macedonia Madagascar Malawi Malaysia Maldives Mali Malta Marshall Islands Mauritania Mauritius Mexico Micronesia Moldova Monaco Mongolia Montenegro Morocco Mozambique Namibia Nauru Nepal Netherlands Netherlands Antilles New Zealand Nicaragua Niger Nigeria North Korea Norway Oman Pakistan Palau Palestinian Territories Panama Papua New Guinea Paraguay Peru Philippines Poland Portugal Qatar Romania Russia Rwanda Saint Kitts and Nevis Saint Lucia Saint Vincent and the Grenadines Samoa San Marino Sao Tome and Principe Saudi Arabia Senegal Serbia Seychelles Sierra Leone Singapore Sint Maarten Slovakia Slovenia Solomon Islands Somalia South Africa South Korea South Sudan Spain Sri Lanka Sudan Suriname Swaziland Sweden Switzerland Syria Taiwan Tajikistan Tanzania Thailand Timor-Leste Togo Tonga Trinidad and Tobago Tunisia Turkey Turkmenistan Tuvalu Uganda Ukraine United Arab Emirates United Kingdom Uruguay Uzbekistan Vanuatu Venezuela Vietnam Yemen Zambia ZimbabweGeneral CommentsOther Attachments*

Upload CV, Statement of Interest, Two (2) Letters of Reference

Submit

FacultyFrancis A. Fakoya, MBChB, MSc, PhDOtimize Y. MAsagbor, DVM,OluwagbemigaAina, PhD.Abdussammad M. Abdussammad, DVM, MSc, PhDStanley Izobo, ANIST, HCST

ContactOluwagbemiga Aina (PhD)Phone: +234 803 394 6735E-mail: gbengaaina2003@yahoo.com

For Hotel Accommodation:

Please visit the website link below for reservation

https://hotels.ng/hotels-in-lagos

UPCOMING TRAININGS: AUGUST-SEPTEMBER, 2018

The following trainings holds between July-August 2018

Ethics of Health Research and Research MethodologyDate: 28th -30th August, 2018Course Fee: N40,000Grant Writing/Manuscript WritingDate: 3rd-5th September, 2018Course Fee: N45,000HIV and TB ManagementDate: 10th-12th September, 2018Course Fee: N40,000Infection Control Practices in HospitalsDate: 18th -20th September, 2018Course Fee: N40,000

For details, interested participants should call 08181512873, 08064484278

Center for Human Virology and Genomics (CHVG) listed as a WHO Prequalification Evaluating Laboratory

Center for Human Virology and Genomics, now a WHO Prequalification Evaluating Laboratory

The Center for Human Virology and Genomics (CHVG) in the Microbiology Department at the Nigerian Institute of Medical Research (NIMR) has just been listed as a WHO Prequalification Evaluating Laboratory. This happened after a successful re-audit of the laboratory to ISO 15189:2012 standard by WHO Geneva on Monday 22nd January 2018. This makes CHVG the first laboratory in West Africa to attain this feat. It therefore means that this laboratory is now listed as a WHO Prequalification Evaluating Laboratory to perform evaluation of In Vitro Diagnostics (IVDs) either coordinated by WHO or commissioned by manufacturer. CHVG would now conduct independent performance evaluations of IVDs which will assist in the diagnosis and/or monitoring of infection with HIV-1, hepatitis B and hepatitis C.

CHVG management, staff and WHO auditors after the closing meeting

The Call by WHO

This laboratory which was recently accredited to ISO 15189:2012 began the journey to being listed as a WHO prequalification evaluating laboratory in December 2016. It was at the satellite session of Strengthening Laboratory Management toward Accreditation (SLMTA) workshop at the conference organized by the African Society of Laboratory Medicine (ASLM) that participants were challenged to attend the WHO session on prequalification evaluation of In vitro Diagnostics. At this session, there was an invitation to laboratories with experience in conducting independent performance evaluations of in vitro diagnostics (IVDs) which assist in the diagnosis and/or monitoring of infection with HIV-1/HIV-2, syphilis, hepatitis B, hepatitis C, Human Papillomavirus (HPV) and G6PD to submit an Expression of Interest for WHO Prequalification Evaluating Laboratories.  To be eligible to apply, laboratories have to be national laboratory that provide testing services to the government in their respective country particularly those located in geographical areas corresponding to the intended setting of use of the IVDs, such as Africa.

 

Activities of CHVG

The CHVG being a national reference laboratory for HIV and viral hepatitis, took up the challenge to submit an expression of interest because of its past experience. The laboratory has evaluated the performance of several IVDs in the past. Since 2004, it has been responsible for evaluating HIV rapid test kits for our national regulatory body in Nigeria. Similarly, it has been evaluating performance of hepatitis B and C rapid test kits for product distributors in the country. The objective of the performance evaluation is to ensure acceptable performance of the test kits before either product registration in the country and/or before they are recommended for mass screening exercise as in the case of hepatitis B and C kits. CHVG has in her biorepository a pool of characterized panels for HIV, hepatitis B and C prepared for this purpose.

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The laboratory is enrolled with the College of American Pathology and Quality Control for Molecular Diagnostics, which are independent external quality assessment providers to ensure her own proficiency. The laboratory has maintained satisfactory performance in these schemes over the years. The laboratory provides routine diagnostic services for HIV-1 confirmation, HIV-1 viral load and early infant diagnosis to our institutional HIV treatment center which cares for over 20,000 patients and patients from other health facilities. CHVG also conducts Hepatitis B and C serology and viral loads for several other hospitals and laboratories across the country. These are the sources for the continuous access to clinical samples from where panels are prepared for performance evaluation. The laboratory has highly skilled and competent personnel who perform these assays and evaluations. The laboratory practices quality management system and had been previously certified to ISO 9001:2008 (1). CHVG is one of the first cohorts of laboratories enrolled in the SLMTA roll out programme in Nigeria in 2010 and it had ASLM Four stars recognition in 2012 during the surveillance audit (2). Recently it obtained ISO 15189 accreditation from the South African National Accreditation Scheme.

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The journey towards WHO listing

As soon as the ASLM conference was over, we completed the WHO online forms and by 23rd December 2017 we submitted an application to WHO Prequalification of In Vitro Diagnostics Programme (3), Geneva. At this time, the documents of the laboratory had been successfully reviewed by the accreditation body. However, WHO required us to make some amendments our method validation reports which we did. The initial audit by WHO was scheduled for a date in May 2017 by which time the pre accreditation assessment by the accrediting body had taken place. Since the laboratory had been successfully assessed for accreditation within a space of about six weeks before this date, we quickly fixed the non-conformities raised and confidently awaited the WHO auditors. When the audit finally took place, several non-conformities were identified that made us almost gave up hope of being selected. Nevertheless, we summoned courage and effected immediate actions, we carried out root cause analyses and submitted the corrective action plans to WHO which were accepted. With the support of our top management, we effected the planned corrective actions within a period of six months. This process improved our system tremendously. The re-audit took place on the 22nd January and we were informed that the corrective action plans were effectively implemented consequently our laboratory has been enlisted as a WHO Evaluating laboratory.

Dr. Rosemary Audu, Deputy Director Research and Laboratory Director CHVG

We therefore enjoin other medical laboratories recently accredited in Africa to take up the challenge to identify long existing gaps that had limited best practices in our health systems. We need to harness our strength to improve medical diagnostics in the continent in order to justify the SLMTA investment made in us to attain our current accreditation status.

References

  1.  Audu RA, Sylvester-Ikondu U , Onwuamah CK, et al. (2012): Experience of Quality Management System in a Clinical Laboratory in Nigeria. Afr J. Lab. Med. 2012;1(1), art. #18, 5 Pages. http://dx.doi. org/10.4102/AJLM.V1I1.18.
  2.  Audu RA, Onubogu CC, Nwokoye NN, Ofuche E, Baboolal S, Oke O, Luman ET and Idigbe EO. Improving quality in national reference laboratories: The role of SLMTA and mentorship. Afr J Lab Med. 2014;3(2), Art. #200, 7 pages. http://dx.doi.org/10.4102/ ajlm.v3i2.200.
  3. WHO Prequalification of In vitro Diagnostics. www. who.int/diagnostics laboratory